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Chemical stability of glass bottles Apr 19, 2018

Good chemical stability principles Glass containers for all types of drugs should have good compatibility with drugs, that is, to ensure that in the production, storage and use of drugs can not be due to the chemical properties of glass containers unstable, the mutual chemical reaction between certain substances caused by the mutation or failure of drugs. For example, blood preparations, vaccines and other high-grade drugs must choose borosilicate glass material glass containers, all kinds of strong acid, strong alkali water needle preparation, especially strong alkali water injection should also choose borosilicate glass material glass containers. China's large number of low boron-silicon glass ampoules used in the preparation of water needle is not appropriate, this type of glass material to gradually to 5.

0 Glass material transition, as soon as possible in line with international standards to ensure that its products in the use of the drug is not off the film, not cloudy, not degenerate. For the general powder injection, oral agent and infusion and other drugs, the use of low borosilicate glass or neutral treatment of sodium-calcium glass can still meet its chemical stability requirements. The degree of erosion of the glass is generally more liquid than solid, alkaline is greater than acid, especially the water injection of strong alkali to medicinal glass bottles of chemical performance requirements.